Asma: este descubrimiento que podría transformar el tratamiento de los pacientes

Un equipo de investigadores franceses ha identificado una molécula responsable de la inflamación alérgica. Un descubrimiento que podría revolucionar los tratamientos para las alergias respiratorias, especialmente las más graves.

¿Podremos pronto tratar completamente el asma o las alergias respiratorias? En cualquier caso, ésta es la esperanza suscitada por un equipo de investigadores franceses del CNRS y del Inserm, que trabajan en el Instituto de Farmacología y Biología Estructural de la Universidad de Toulouse III. En un estudio codirigido por dos biólogos, Corinne Cayrol (CNRS) y Jean-Philippe Girard (Inserm), este último explica haber identificado «una de las moléculas responsables de desencadenar la inflamación en el origen de las enfermedades respiratorias alérgicas, como el asma». y rinitis alérgica. Este descubrimiento en el campo del asma abre nuevas posibilidades para el tratamiento de los pacientes.

En concreto, estos investigadores identificaron la existencia de una molécula de tipo alarmina, denominada TL1A, emitida por los pulmones cuando están expuestos a un alérgeno (hongos en el aire o incluso polen). Alarmina, porque es ésta la que envía ondas de señales de alarma al sistema inmunológico, desencadenando una auténtica “cascada de reacciones en cadena responsables de la inflamación alérgica”, explica el estudio. Este hallazgo refuerza la importancia del descubrimiento asma en la investigación actual.

La identificación de esta molécula de alarmina podría transformar por completo la forma de curar las alergias respiratorias. «Si conseguimos bloquear estas señales de alarma, podremos bloquear toda la cascada que se deriva de ellas. Mientras que, si bloqueamos los efectos más tarde, el tratamiento no será tan eficaz», confirma el biólogo Jean-Philippe Girard, quien codirigió el estudio.

El CNRS y el Inserm aseguran así en su estudio que “en unos años, los tratamientos basados ​​en anticuerpos que bloqueen la alarmina TL1A podrían beneficiar a los pacientes que padecen asma grave u otras enfermedades alérgicas”. Una observación apoyada por Jean-Philippe Girard. «Estamos ante un descubrimiento importante, con una aplicación que puede ser muy rápida. Pero ya sabemos que este tipo de tratamiento ya funciona y que no es peligroso, porque se utiliza especialmente en el intestino, contra la enfermedad de Crohn. Dentro de cinco años, podemos pensar legítimamente que los pacientes con asma grave podrán ser tratados de esta manera. Este descubrimiento asma es un paso significativo hacia tratamientos más efectivos.

Sin embargo, el biólogo del Inserm quiere ser cauteloso: estos avances aún están lejos de significar que todas las personas afectadas por alergias respiratorias se curarán en una década. «Estos tratamientos serían actualmente muy costosos. Se reservarían especialmente para los casos graves de asma, que corren peligro para la vida del paciente y que son resistentes a los tratamientos existentes», insiste Jean-Philippe Girard.

30 consejos de expertos para proteger su vida del invierno

Las formas más graves de asma son responsables de varios centenares de muertes cada año”. Incluso si el mecanismo seguiría siendo el mismo para alergias menos peligrosas. “A condición de encontrar una molécula que cueste mucho menos”, concluye Jean-Philippe Girard.

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Doing the best at this moment puts you in the best place for the next moment! Oprah Winfrey

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Success is largely a matter of holding on after others have let go!

• A year from now you may wish you had started today.
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• Success is the sum of small efforts, repeated day-in and day-out.
• I find that the harder I work, the more luck I seem to have.
• If people did not do silly things, nothing intelligent would ever get done.
• Before anything else, preparation is the key to success.

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Action is the foundational key to all success

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Success is how high you bounce when you hit bottom

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3 cambios simples para mejorar la salud del corazón

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Great things in business are never done by one person. They’re done by a team of people. Steve Jobs

They never said winning was easy. Some people can’t manejar el éxito, yo puedo. You see the hedges, how I got it shaped up? It’s importante shape up your hedges, it’s like getting a haircut, stay fresh. I told you all this before, when you have a swimming pool, do not use chlorine, use salt water, the healing, salt water is the healing. Look at the sunset, life is amazing, life is beautiful, life is what you make it. Egg whites, turkey sausage, wheat toast, water. Of course they don’t want us to eat our breakfast, so we are going to enjoy our breakfast.

F.J.D.L.A.

REDACTOR JEFE

Graduado por la Universidad Internacional de la Rioja. Formó parte de la primera edición de 7 Noticias y clasificados. Diversos estudios en Derecho, Psicología e inserción laboral. Desde entonces informa sobre noticias nacionales, locales y deportivas.Soy Especialista SEO, Copywriter

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